In this paper, we address the problem of statistical learning for multi- topic text categorization (MTC), whose goal is to choose all relevant top- ics (a label) from a given set of topics. The proposed algorithm, Max- imal Margin Labeling (MML), treats all possible labels as independent classes and learns a multi-class classifier on the induced multi-class cate- gorization problem. To cope with the data sparseness caused by the huge number of possible labels, MML combines some prior knowledge about label prototypes and a maximal margin criterion in a novel way. Experi- ments with multi-topic Web pages show that MML outperforms existing learning algorithms including Support Vector Machines. This paper addresses the problem of learning for multi-topic text categorization (MTC), whose goal is to select all topics relevant to a text from a given set of topics.